HIV Target gene Detail Information

> ACKR2 Gene Search Result

Gene Information

Gene Name	ACKR2
Gene ID	1238
Gene Full Name	atypical chemokine receptor 2
Gene Alias	D6; hD6; CCR9; CCBP2; CCR10; CMKBR9
Transcripts	ENSG00000144648
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Vesicles;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	G-protein coupled receptors, Predicted membrane proteins
Uniport_ID	O00590
HGNC ID	HGNC:1565
VEGA ID	OTTHUMG00000186377
OMIM ID	602648
String ID	9606.ENSP00000416996
PharmGKB ID	PA26139

Target gene [ACKR2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009409	chr3	5	5	1	11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ACKR2 expression and immune infiltrating cell level correlation result in HIV+ samples
ACKR2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).