Gene Information
Gene Name
|
ACE |
Gene ID
|
1636
|
Gene Full Name
|
angiotensin I converting enzyme |
Gene Alias
|
DCP; ACE1; DCP1; CD143 |
Transcripts
|
ENSG00000159640
|
Virus
|
HPV |
Gene Type
|
protein coding |
HPA Location Info
|
Vesicles;Predicted to be secreted;
|
Membrane Info
|
Predicted membrane proteins |
HPA Protein Class Info
|
Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins |
Uniport_ID
|
P12821
|
HGNC ID
|
HGNC:2707
|
VEGA ID
|
OTTHUMG00000154927
|
OMIM ID
|
106180 |
String ID
|
9606.ENSP00000290866
|
Drugbank ID
|
BE0000221
|
PharmGKB ID
|
PA139
|
Target gene [ACE] related to VISs
DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
5200407 |
chr17 |
12 |
3 |
|
15 |
View |
Relationship between gene expression and immune infiltrating cell level
Data ID |
Disease |
Sample number |
Sample type |
GSE140662 (GEO) |
Condyloma Acuminatum |
8 |
Condyloma acuminata (HPV+)(5), Skin(3) |
GSE40774 (GEO) |
Head and neck squamous cell carcinoma |
134 |
Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1) |
GSE55546 (GEO) |
Oropharyngeal squamous cell carcinoma |
16 |
Oropharyngeal cancers (HPV+)(12), Normal (4) |
GSE55544 (GEO) |
Oropharyngeal squamous cell carcinoma |
23 |
Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8) |
GSE55542 (GEO) |
Oropharyngeal squamous cell carcinoma |
36 |
Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16) |
GSE138080 (GEO) |
Cervical intraepithelial neoplasia |
25 |
Normal (10), Cervical intraepithelial neoplasia (HPV+)(15) |
GSE51993 (GEO) |
Cervical intraepithelial neoplasia |
24 |
Cervical intraepithelial neoplasia (HPV+)(17), Normal(7) |
HNSC (TCGA) |
Head and Neck squamous cell carcinoma |
566 |
Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44) |
> Dataset: GSE140662
|
HeatMap of cell type fractions in all samples
|
Lollipop of ACE expression and immune infiltrating cell level correlation result in HPV+ samples
|
ACE expression: Low -> High
|
|
|
> Dataset: GSE40774
|
HeatMap of cell type fractions in all samples
|
Lollipop of ACE expression and immune infiltrating cell level correlation result in HPV+ samples
|
ACE expression: Low -> High
|
|
|
> Dataset: GSE55546
|
HeatMap of cell type fractions in all samples
|
Lollipop of ACE expression and immune infiltrating cell level correlation result in HPV+ samples
|
ACE expression: Low -> High
|
|
|
> Dataset: GSE55544
|
HeatMap of cell type fractions in all samples
|
Lollipop of ACE expression and immune infiltrating cell level correlation result in HPV+ samples
|
ACE expression: Low -> High
|
|
|
> Dataset: GSE55542
|
HeatMap of cell type fractions in all samples
|
Lollipop of ACE expression and immune infiltrating cell level correlation result in HPV+ samples
|
ACE expression: Low -> High
|
|
|
> Dataset: GSE138080
|
HeatMap of cell type fractions in all samples
|
Lollipop of ACE expression and immune infiltrating cell level correlation result in HPV+ samples
|
ACE expression: Low -> High
|
|
|
> Dataset: GSE51993
|
HeatMap of cell type fractions in all samples
|
Lollipop of ACE expression and immune infiltrating cell level correlation result in HPV+ samples
|
ACE expression: Low -> High
|
|
|
> Dataset: HNSC
|
HeatMap of cell type fractions in all samples
|
Lollipop of ACE expression and immune infiltrating cell level correlation result in HPV+ samples
|
ACE expression: Low -> High
|
|
|
|
|