HIV Target gene Detail Information

> ACADM Gene Search Result


Gene Information
Gene Name ACADM
Gene ID 34
Gene Full Name acyl-CoA dehydrogenase medium chain
Gene Alias MCAD; ACAD1; MCADH
Transcripts ENSG00000117054
Virus HIV
Gene Type protein coding
HPA Location Info Mitochondria;
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID P11310
HGNC ID HGNC:89
VEGA ID OTTHUMG00000009784
OMIM ID 607008
String ID 9606.ENSP00000359871
Drugbank ID BE0001745
PharmGKB ID PA24425
Target gene [ACADM] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4007290 chr1 18 2 20 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ACADM expression and immune infiltrating cell level correlation result in HIV+ samples
ACADM expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ACADM expression and immune infiltrating cell level correlation result in HIV+ samples
ACADM expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).