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HBV Target gene Detail Information

> ABL2 Gene Search Result


Gene Information
Gene Name ABL2
Gene ID 27
Gene Full Name ABL proto-oncogene 2, non-receptor tyrosine kinase
Gene Alias ARG; ABLL
Transcripts ENSG00000143322
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;
HPA Protein Class Info Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins
Gene Function Oncogene
Uniport_ID P42684
HGNC ID HGNC:77
VEGA ID OTTHUMG00000035199
OMIM ID 164690
String ID 9606.ENSP00000427562
Drugbank ID BE0000435
Drug (Cytoscape Annotation) Axitinib;Nilotinib;Crizotinib;Vandetanib;Sunitinib Malate;Dasatinib;Erlotinib Hydrochloride;Imatinib Mesylate;Bosutinib
PharmGKB ID PA24414
Target gene [ABL2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011538 chr1 7 1 1 9 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ABL2 expression and immune infiltrating cell level correlation result in HBV+ samples
ABL2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).