HBV Target gene Detail Information

> ABI2 Gene Search Result


Gene Information
Gene Name ABI2
Gene ID 10152
Gene Full Name abl interactor 2
Gene Alias AIP1; ABI-2; ABI2B; AIP-1; AblBP3; argBP1; SSH3BP2; argBPIA; argBPIB
Transcripts ENSG00000138443
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;Vesicles;
HPA Protein Class Info Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q9NYB9
HGNC ID HGNC:24011
VEGA ID OTTHUMG00000132879
OMIM ID 606442
String ID 9606.ENSP00000295851
PharmGKB ID PA134977642
Target gene [ABI2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006144 chr2 37 5 42 View
1017260 chr2 1 1 View
1402331 chr2 37 5 42 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ABI2 expression and immune infiltrating cell level correlation result in HBV+ samples
ABI2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).