HIV Target gene Detail Information

> ABHD12 Gene Search Result

Gene Information

Gene Name	ABHD12
Gene ID	26090
Gene Full Name	abhydrolase domain containing 12
Gene Alias	PHARC; ABHD12A; BEM46L2; C20orf22; dJ965G21.2
Transcripts	ENSG00000100997
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q8N2K0
HGNC ID	HGNC:15868
VEGA ID	OTTHUMG00000032121
OMIM ID	613599
String ID	9606.ENSP00000365725
PharmGKB ID	PA25738

Target gene [ABHD12] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011739	chr20	6			6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ABHD12 expression and immune infiltrating cell level correlation result in HIV+ samples
ABHD12 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ABHD12 expression and immune infiltrating cell level correlation result in HIV+ samples
ABHD12 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).