HBV Target gene Detail Information

> ABCG8 Gene Search Result

Gene Information

Gene Name	ABCG8
Gene ID	64241
Gene Full Name	ATP binding cassette subfamily G member 8
Gene Alias	GBD4; STSL
Transcripts	ENSG00000143921
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID	Q9H221
HGNC ID	HGNC:13887
VEGA ID	OTTHUMG00000128756
OMIM ID	605460
String ID	9606.ENSP00000272286
Drugbank ID	BE0004751
PharmGKB ID	PA24412

Target gene [ABCG8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000699	chr2	128	988	469	1585	View
1001012	chr2	132	733	285	1150	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ABCG8 expression and immune infiltrating cell level correlation result in HBV+ samples
ABCG8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).