HBV Target gene Detail Information

> ABCD3 Gene Search Result


Gene Information
Gene Name ABCD3
Gene ID 5825
Gene Full Name ATP binding cassette subfamily D member 3
Gene Alias ZWS2; ABC43; CBAS5; PMP70; PXMP1
Transcripts ENSG00000117528
Virus HBV
Gene Type protein coding
HPA Location Info Peroxisomes;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID P28288
HGNC ID HGNC:67
VEGA ID OTTHUMG00000010717
OMIM ID 170995
String ID 9606.ENSP00000359233
PharmGKB ID PA24402
Target gene [ABCD3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007950 chr1 12 11 23 View
1007951 chr1 12 11 23 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ABCD3 expression and immune infiltrating cell level correlation result in HBV+ samples
ABCD3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).