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HBV Target gene Detail Information

> ABCC8 Gene Search Result


Gene Information
Gene Name ABCC8
Gene ID 6833
Gene Full Name ATP binding cassette subfamily C member 8
Gene Alias HI; SUR; HHF1; MRP8; PHHI; SUR1; ABC36; HRINS; TNDM2; SUR1delta2
Transcripts ENSG00000006071
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoli;Cytosol;Golgi apparatus;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters
Uniport_ID Q09428
HGNC ID HGNC:59
VEGA ID OTTHUMG00000166316
OMIM ID 600509
String ID 9606.ENSP00000303960
Drugbank ID BE0000207; BE0008670
PharmGKB ID PA24395
Target gene [ABCC8] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010010 chr11 8 5 13 View
1012363 chr11 4 3 7 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ABCC8 expression and immune infiltrating cell level correlation result in HBV+ samples
ABCC8 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).