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HBV Target gene Detail Information

> ABCC6 Gene Search Result


Gene Information
Gene Name ABCC6
Gene ID 368
Gene Full Name ATP binding cassette subfamily C member 6
Gene Alias ARA; PXE; MLP1; MRP6; PXE1; URG7; ABC34; GACI2; MOATE; MOAT-E; EST349056
Transcripts ENSG00000275331
Virus HBV
Gene Type protein coding
HPA Location Info Plasma membrane;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID O95255
HGNC ID HGNC:57
VEGA ID OTTHUMG00000191118
OMIM ID 603234
String ID 9606.ENSP00000205557
Drugbank ID BE0003640
PharmGKB ID PA58
Target gene [ABCC6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011703 chr16 4 4 8 View
1012662 chr16 3 3 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ABCC6 expression and immune infiltrating cell level correlation result in HBV+ samples
ABCC6 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).