HBV Target gene Detail Information

> ABCC5 Gene Search Result

Gene Information

Gene Name	ABCC5
Gene ID	10057
Gene Full Name	ATP binding cassette subfamily C member 5
Gene Alias	MRP5; SMRP; ABC33; MOATC; MOAT-C; pABC11; EST277145
Transcripts	ENSG00000114770
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cell Junctions;Plasma membrane;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	O15440
HGNC ID	HGNC:56
VEGA ID	OTTHUMG00000156871
OMIM ID	605251
String ID	9606.ENSP00000333926
Drugbank ID	BE0003639
PharmGKB ID	PA395

Target gene [ABCC5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003634	chr3	37	83		120	View
1008707	chr3	12	4	3	19	View
1012207	chr3	7			7	View
1403330	chr3	12	4	3	19	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ABCC5 expression and immune infiltrating cell level correlation result in HBV+ samples
ABCC5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).