HBV Target gene Detail Information

> ABCC2 Gene Search Result

Gene Information

Gene Name	ABCC2
Gene ID	1244
Gene Full Name	ATP binding cassette subfamily C member 2
Gene Alias	DJS; MRP2; cMRP; ABC30; CMOAT
Transcripts	ENSG00000023839
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q92887
HGNC ID	HGNC:53
VEGA ID	OTTHUMG00000018895
OMIM ID	601107
String ID	9606.ENSP00000359478
Drugbank ID	BE0001069
PharmGKB ID	PA116

Target gene [ABCC2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002556	chr10	25	113	110	248	View
1015133	chr10	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ABCC2 expression and immune infiltrating cell level correlation result in HBV+ samples
ABCC2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).