HBV Target gene Detail Information

> ABCC1 Gene Search Result

Gene Information

Gene Name	ABCC1
Gene ID	4363
Gene Full Name	ATP binding cassette subfamily C member 1
Gene Alias	MRP; ABCC; GS-X; MRP1; ABC29
Transcripts	ENSG00000278183
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Cell Junctions;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters
Uniport_ID	P33527
HGNC ID	HGNC:51
VEGA ID	OTTHUMG00000191115
OMIM ID	158343
String ID	9606.ENSP00000382342
Drugbank ID	BE0000785
PharmGKB ID	PA244

Target gene [ABCC1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008150	chr16	20	2		22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ABCC1 expression and immune infiltrating cell level correlation result in HBV+ samples
ABCC1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).