HIV Target gene Detail Information

> ABCB7 Gene Search Result

Gene Information

Gene Name	ABCB7
Gene ID	22
Gene Full Name	ATP binding cassette subfamily B member 7
Gene Alias	ABC7; ASAT; Atm1p; EST140535
Transcripts	ENSG00000131269
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	O75027
HGNC ID	HGNC:48
VEGA ID	OTTHUMG00000021862
OMIM ID	300135
String ID	9606.ENSP00000253577
PharmGKB ID	PA24389

Target gene [ABCB7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013128	chrX	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ABCB7 expression and immune infiltrating cell level correlation result in HIV+ samples
ABCB7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ABCB7 expression and immune infiltrating cell level correlation result in HIV+ samples
ABCB7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).