HIV Target gene Detail Information

> ABCB11 Gene Search Result

Gene Information

Gene Name	ABCB11
Gene ID	8647
Gene Full Name	ATP binding cassette subfamily B member 11
Gene Alias	BSEP; PGY4; SPGP; ABC16; BRIC2; PFIC2; PFIC-2
Transcripts	ENSG00000276582
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID	O95342
HGNC ID	HGNC:42
VEGA ID	OTTHUMG00000175312
OMIM ID	603201
String ID	9606.ENSP00000263817
Drugbank ID	BE0000703
PharmGKB ID	PA374

Target gene [ABCB11] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009680	chr2	8	2	1	11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ABCB11 expression and immune infiltrating cell level correlation result in HIV+ samples
ABCB11 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).