Home
Virus
Gene
Disease
Dataset
Download
Help
 
HTLV1 Target gene Detail Information

> ABCB1 Gene Search Result


Gene Information
Gene Name ABCB1
Gene ID 5243
Gene Full Name ATP binding cassette subfamily B member 1
Gene Alias CLCS; MDR1; P-GP; PGY1; ABC20; CD243; GP170
Transcripts ENSG00000085563
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoplasm;Plasma membrane;Focal adhesion sites;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID P08183
HGNC ID HGNC:40
VEGA ID OTTHUMG00000023393
OMIM ID 171050
String ID 9606.ENSP00000478255
Drugbank ID BE0001032
PharmGKB ID PA267
Target gene [ABCB1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6031206 chr7 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ABCB1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ABCB1 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ABCB1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ABCB1 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of ABCB1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ABCB1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).