HBV Target gene Detail Information

> ABCA4 Gene Search Result


Gene Information
Gene Name ABCA4
Gene ID 24
Gene Full Name ATP binding cassette subfamily A member 4
Gene Alias FFM; RMP; ABCR; RP19; STGD; ABC10; ARMD2; CORD3; STGD1
Transcripts ENSG00000198691
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID P78363
HGNC ID HGNC:34
VEGA ID OTTHUMG00000010622
OMIM ID 601691
String ID 9606.ENSP00000359245
PharmGKB ID PA24379
Target gene [ABCA4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005383 chr1 42 12 1 55 View
1009102 chr1 4 13 17 View
1009753 chr1 3 11 14 View
1402219 chr1 4 13 17 View
1402220 chr1 3 11 14 View
1402936 chr1 42 12 1 55 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ABCA4 expression and immune infiltrating cell level correlation result in HBV+ samples
ABCA4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).