HIV Target gene Detail Information

> ABCA3 Gene Search Result

Gene Information

Gene Name	ABCA3
Gene ID	21
Gene Full Name	ATP binding cassette subfamily A member 3
Gene Alias	ABC3; ABC-C; SMDP3; LBM180; EST111653
Transcripts	ENSG00000167972
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID	Q99758
HGNC ID	HGNC:33
VEGA ID	OTTHUMG00000128845
OMIM ID	601615
String ID	9606.ENSP00000301732
Drugbank ID	BE0003671
PharmGKB ID	PA24378

Target gene [ABCA3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008899	chr16	6	4	3	13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ABCA3 expression and immune infiltrating cell level correlation result in HIV+ samples
ABCA3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ABCA3 expression and immune infiltrating cell level correlation result in HIV+ samples
ABCA3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).