HBV Target gene Detail Information

> ABCA12 Gene Search Result


Gene Information
Gene Name ABCA12
Gene ID 26154
Gene Full Name ATP binding cassette subfamily A member 12
Gene Alias LI2; ICR2B; ARCI4A; ARCI4B
Transcripts ENSG00000144452
Virus HBV
Gene Type protein coding
HPA Location Info Plasma membrane;Vesicles;Cytosol;Nucleoli;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID Q86UK0
HGNC ID HGNC:14637
VEGA ID OTTHUMG00000154801
OMIM ID 607800
String ID 9606.ENSP00000272895
PharmGKB ID PA29604
Target gene [ABCA12] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1017166 chr2 1 1 View
1019408 chr2 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ABCA12 expression and immune infiltrating cell level correlation result in HBV+ samples
ABCA12 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).