HIV Target gene Detail Information

> AASS Gene Search Result

Gene Information

Gene Name	AASS
Gene ID	10157
Gene Full Name	aminoadipate-semialdehyde synthase
Gene Alias	LKRSDH; LORSDH; LKR/SDH
Transcripts	ENSG00000008311
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;Vesicles;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q9UDR5
HGNC ID	HGNC:17366
VEGA ID	OTTHUMG00000157058
OMIM ID	605113
String ID	9606.ENSP00000377040
Drugbank ID	BE0000073
PharmGKB ID	PA24369

Target gene [AASS] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004553	chr7	31	10	1	42	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of AASS expression and immune infiltrating cell level correlation result in HIV+ samples
AASS expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).