HBV Target gene Detail Information

> AASDH Gene Search Result

Gene Information

Gene Name	AASDH
Gene ID	132949
Gene Full Name	aminoadipate-semialdehyde dehydrogenase
Gene Alias	LYS2; ACSF4; NRPS998; NRPS1098
Transcripts	ENSG00000157426
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q4L235
HGNC ID	HGNC:23993
VEGA ID	OTTHUMG00000128841
OMIM ID	614365
String ID	9606.ENSP00000205214
PharmGKB ID	PA162375178

Target gene [AASDH] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003666	chr4	82	32	4	118	View
1006174	chr4	40	1	1	42	View
1006694	chr4	34		1	35	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of AASDH expression and immune infiltrating cell level correlation result in HBV+ samples
AASDH expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).