HTLV1 Target gene Detail Information

> AAGAB Gene Search Result

Gene Information

Gene Name	AAGAB
Gene ID	79719
Gene Full Name	alpha and gamma adaptin binding protein
Gene Alias	p34; KPPP1; PPKP1; PPKP1A
Transcripts	ENSG00000103591
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Nuclear speckles;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q6PD74
HGNC ID	HGNC:25662
VEGA ID	OTTHUMG00000172246
OMIM ID	614888
String ID	9606.ENSP00000261880
PharmGKB ID	PA165478457

Target gene [AAGAB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6008847	chr15	42			42	View
6014878	chr15	5	10		15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of AAGAB expression and immune infiltrating cell level correlation result in HTLV1+ samples
AAGAB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).