Mutation Information
Mutation Site
|
Y44A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Tat |
Literature Information
PubMed PMID
|
32824587
|
Published Year
|
2020 |
Journal
|
International journal of molecular sciences |
Title
|
Y44A Mutation in the Acidic Domain of HIV-2 Tat Impairs Viral Reverse Transcription and LTR-Transactivation. |
Author
|
Szojka Z,Mótyán JA,Miczi M,Mahdi M,Tőzsér J |
Evidence
|
Here, we describe Y44A-inactivating mutation of HIV-2 Tat, studying its effect on capsid production, reverse transcription, and the efficiency of proviral transcription.
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