Mutation Information
Mutation Site
|
Y379A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
E1 |
Genotype/Subtype
|
HPV16 |
Literature Information
PubMed PMID
|
24456830
|
Published Year
|
2014 |
Journal
|
Virology journal |
Title
|
Replication interference between human papillomavirus types 16 and 18 mediated by heterologous E1 helicases. |
Author
|
Mori S,Kusumoto-Matsuo R,Ishii Y,Takeuchi T,Kukimoto I |
Evidence
|
HPV16 E1 co-precipitated with HPV18 E1 in the cell lysates, and an HPV16 E1 mutant Y379A, which bound to HPV18 E1 less efficiently, failed to inhibit HPV18 replication.
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