|
Mutation Information
|
Mutation Site
|
Y251N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
LMP1 |
|
Viral Reference
|
NC_007605.1;
DQ279927.1;
V01555.2;
AY961628.3;
HQ020558.1;
JQ009376.2 |
|
Country
|
Beijing; China |
Literature Information
|
PubMed PMID
|
27189712
|
|
Disease
|
Lung carcinoma
|
|
Published Year
|
2016 |
|
Journal
|
Scientific reports |
|
Title
|
Identification and Characterization of Epstein-Barr Virus Genomes in Lung Carcinoma Biopsy Samples by Next-Generation Sequencing Technology. |
|
Author
|
Wang S,Xiong H,Yan S,Wu N,Lu Z |
|
Evidence
|
The N-terminal cytoplasmic tail and transmembrane domain displayed complete conservation among LC strains, while the CTARs demonstrated more diversity with two amino acids that were not present in previously published EBV sequences, including the substitution Tyr at Asn251 observed in LC4 and the substitution Gln at His308 observed in LC1.
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|
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EBV Mutation Detail Information