HBV Mutation Detail Information

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Mutation Information
Mutation Site Y206C
Mutation Type Amino acid level
Gene/Protein/Region Type S
Genotype/Subtype D
Viral Reference X68292.1
Country Italy
Literature Information
PubMed PMID 25452041
Disease Chronic hepatitis B
Published Year 2015
Journal The Journal of infection
Title Specific mutations in the C-terminus domain of HBV surface antigen significantly correlate with low level of serum HBV-DNA in patients with chronic HBV infection.
Author Mirabelli C,Surdo M,Van Hemert F,Lian Z,Salpini R,Cento V,Cortese MF,Aragri M,Pollicita M,Alteri C,Bertoli A,Berkhout B,Micheli V,Gubertini G,Santoro MM,Romano S,Visca M,Bernassola M,Longo R,De Sanctis GM,Trimoulet P,Fleury H,Marino N,Mazzotta F,Cappiello G,Spanò A,Sarrecchia C,Zhang JM,Andreoni M,Angelico M,Verheyen J,Perno CF,Svicher V
Evidence Results: Specific HBsAg-mutations (M197T,-S204N-Y206C/H-F220L) were significantly correlated with serum HBV-DNA <2000 IU/ml (posterior-probability>90%, P < 0.05). 

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation