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Mutation Information
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Mutation Site
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Y200E |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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BZLF1 |
Literature Information
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PubMed PMID
|
9123876
|
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Published Year
|
1997 |
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Journal
|
Virology |
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Title
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The bZip dimerization domain of the Epstein-Barr virus BZLF1 (Z) protein mediates lymphoid-specific negative regulation. |
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Author
|
Hong Y,Holley-Guthrie E,Kenney S |
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Evidence
|
In lymphoid cells, a Z mutant which has been altered at amino acid 200 (tyrosine to glutamic acid) transactivates both the early BMRF1 promoter and the immediate-early BZLF1 promoter (Zp) four- to fivefold better than wild-type Z.
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EBV Mutation Detail Information