|
Mutation Information
|
Mutation Site
|
Y188L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
U46016;
AY242579-AY242597;
KU319672-KU319798;
AY772699;
AF067155;
U52953;
AX149771 |
|
Relevant Drug
|
etravirine(ETR);doravirine (DOR);efavirenz (EFV);nevirapine (NPV);rilpivirine (RPV) |
|
Country
|
Ethiopia |
Literature Information
|
PubMed PMID
|
32993693
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Retrovirology |
|
Title
|
Increased HIV-1 pretreatment drug resistance with consistent clade homogeneity among ART-naive HIV-1 infected individuals in Ethiopia. |
|
Author
|
Kiros M,Alemayehu DH,Geberekidan E,Mihret A,Maier M,Abegaz WE,Mulu A |
|
Evidence
|
The most frequently observed NNRTIs-associated mutations common to both algorithms were K103N (2%), Y188L (2%), K101E (2%), and V106A (2%), while E138A (2%) was observed according to IAS-USA only.
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HIV Mutation Detail Information