HIV Mutation Detail Information

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Mutation Information

Mutation Site	Y188L
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Country	Uganda

Literature Information

PubMed PMID	32005262
Disease	HIV infection/AIDS
Published Year	2020
Journal	AIDS research and therapy
Title	Comparison of HIV drug resistance profiles across HIV-1 subtypes A and D for patients receiving a tenofovir-based and zidovudine-based first line regimens in Uganda.
Author	Ayitewala A,Kyeyune F,Ainembabazi P,Nabulime E,Kato CD,Nankya I
Evidence	Within the NNRTI class, G190 mutations (69.1%, p = 0.015), Y181C (78.6%, p = 0.008), L100I (82.4%, p = 0.019) were significantly more in the TDF/3TC/EFV group whereas mutation K238T (71.4%, p = 0.035) was significantly more in the AZT/3TC/EFV group (Fig. 2).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation