|
Mutation Information
|
Mutation Site
|
Y188L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NNRTIs |
Literature Information
|
PubMed PMID
|
32004936
|
|
Published Year
|
2020 |
|
Journal
|
European journal of medicinal chemistry |
|
Title
|
Discovery, synthesis, and optimization of an N-alkoxy indolylacetamide against HIV-1 carrying NNRTI-resistant mutations from the Isatis indigotica root. |
|
Author
|
Xu C,Xin Y,Chen M,Ba M,Guo Q,Zhu C,Guo Y,Shi J |
|
Evidence
|
Among these, K103N, Y181C or Y188L, carried by RT, are the most prevalent mutants.
|
|
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HIV Mutation Detail Information