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Mutation Information
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Mutation Site
|
Y188L |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Genotype/Subtype
|
D |
|
Relevant Drug
|
NNRTIs |
Literature Information
|
PubMed PMID
|
30648124
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
|
Journal
|
Open forum infectious diseases |
|
Title
|
Development of the R263K Mutation to Dolutegravir in an HIV-1 Subtype D Virus Harboring 3 Class-Drug Resistance. |
|
Author
|
Ahmed N,Flavell S,Ferns B,Frampton D,Edwards SG,Miller RF,Grant P,Nastouli E,Gupta RK |
|
Evidence
|
At that time, resistance testing showed NRTI (M184V, T69D, T215S, D67N, K219Q), NNRTI (Y181C, Y188L, H221Y) and PI (L10I, D30N, K20T, L33F, K43T, N88D) resistance, with PI resistance to nelfinavir.
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HIV Mutation Detail Information