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Mutation Information
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Mutation Site
|
Y188L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NNRTIs |
|
Country
|
Taiwan(China) |
Literature Information
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PubMed PMID
|
29861843
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
Oncotarget |
|
Title
|
HIV-1 integrase strand-transfer inhibitor resistance in southern Taiwan. |
|
Author
|
Tsai HC,Chen IT,Wu KS,Tseng YT,Sy CL,Chen JK,Lee SS,Chen YS |
|
Evidence
|
The most common drug resistance-associated mutations to NRTIs were M184V (1.1%) and K65R (1.1%), while those for NNRTIs were V179D (4.9%), V106I (3.3%), K103N (1.6%) and Y188L/V90I (1.1%) and those for PIs were L10I (16.3%), A71T (7.1%), and L10V (4.9%) (Figure 1).
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HIV Mutation Detail Information