HIV Mutation Detail Information

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Mutation Information
Mutation Site Y188L
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug NNRTIs
Country Taiwan(China)
Literature Information
PubMed PMID 29861843
Disease HIV infection/AIDS
Published Year 2018
Journal Oncotarget
Title HIV-1 integrase strand-transfer inhibitor resistance in southern Taiwan.
Author Tsai HC,Chen IT,Wu KS,Tseng YT,Sy CL,Chen JK,Lee SS,Chen YS
Evidence The most common drug resistance-associated mutations to NRTIs were M184V (1.1%) and K65R (1.1%), while those for NNRTIs were V179D (4.9%), V106I (3.3%), K103N (1.6%) and Y188L/V90I (1.1%) and those for PIs were L10I (16.3%), A71T (7.1%), and L10V (4.9%) (Figure 1).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation