|
Mutation Information
|
Mutation Site
|
Y188L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
C |
|
Relevant Drug
|
nevirapine (NPV) |
|
Country
|
Malawi |
Literature Information
|
PubMed PMID
|
21487249
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2011 |
|
Journal
|
AIDS (London, England) |
|
Title
|
Analysis of nevirapine resistance in HIV-infected infants who received extended nevirapine or nevirapine/zidovudine prophylaxis. |
|
Author
|
Fogel J,Hoover DR,Sun J,Mofenson LM,Fowler MG,Taylor AW,Kumwenda N,Taha TE,Eshleman SH |
|
Evidence
|
Five infants had NVP resistance mutations other than K103N and Y181C detected by ViroSeq at 14 weeks (V106A, Y188C/L, G190A) in the absence of K103N or Y181C.
|
|
|
HIV Mutation Detail Information