HIV Mutation Detail Information

> Y188C Search Result

Mutation Information

Mutation Site	Y188C
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NNRTIs
Country	Spain

Literature Information

PubMed PMID	32929472
Disease	HIV infection/AIDS
Published Year	2020
Journal	The Journal of antimicrobial chemotherapy
Title	Primary resistance to integrase strand transfer inhibitors in Spain using ultrasensitive HIV-1 genotyping.
Author	Casadellà M,Santos JR,Noguera-Julian M,Micán-Rivera R,Domingo P,Antela A,Portilla J,Sanz J,Montero-Alonso M,Navarro J,Masiá M,Valcarce-Pardeiro N,Ocampo A,Pérez-Martínez L,Pasquau J,Vivancos MJ,Imaz A,Carmona-Oyaga P,Muñoz-Medina L,Villar-García J,Barrufet P,Paredes R,INSTINCT Study Group.
Evidence	A total of 6/146 (4.1%) samples had low-frequency NNRTI-associated mutations, two of which had K103S and Y188C mutations in >5%–20% of their viral population while four had other NNRTI-associated mutations in 1%–5% of their viral population (Figure 2b).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation