|
Mutation Information
|
Mutation Site
|
Y188C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NNRTIs |
|
Country
|
India |
Literature Information
|
PubMed PMID
|
30477526
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
AIDS research and therapy |
|
Title
|
Long-term virological outcome in children receiving first-line antiretroviral therapy. |
|
Author
|
Chandrasekaran P,Shet A,Srinivasan R,Sanjeeva GN,Subramanyan S,Sunderesan S,Ramesh K,Gopalan B,Suresh E,Poornagangadevi N,Hanna LE,Chandrasekar C,Wanke C,Swaminathan S |
|
Evidence
|
K103N (48%), Y181C (37%), G190A/S (25%), Y188C/L (10%), V106M/A (8%), K65R (8%) and L100I (4%) were the major NNRTI DRMs observed in these 52 children (Fig. 3).
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HIV Mutation Detail Information