|
Mutation Information
|
Mutation Site
|
Y188C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NNRTIs |
Literature Information
|
PubMed PMID
|
20102272
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2010 |
|
Journal
|
The Journal of infectious diseases |
|
Title
|
Low frequency nonnucleoside reverse-transcriptase inhibitor-resistant variants contribute to failure of efavirenz-containing regimens in treatment- experienced patients. |
|
Author
|
Halvas EK,Wiegand A,Boltz VF,Kearney M,Nissley D,Wantman M,Hammer SM,Palmer S,Vaida F,Coffin JM,Mellors JW |
|
Evidence
|
K103N clustered closely (bootstrap value 96) with sequences at failure containing K103N linked to Y188C or M230L.
|
|
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HIV Mutation Detail Information