|
Mutation Information
|
Mutation Site
|
Y181Y |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
A |
|
Relevant Drug
|
nevirapine (NPV) |
|
Country
|
Kenya |
Literature Information
|
PubMed PMID
|
27231099
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2016 |
|
Journal
|
Journal of the International AIDS Society |
|
Title
|
Treatment failure and drug resistance in HIV-positive patients on tenofovir-based first-line antiretroviral therapy in western Kenya. |
|
Author
|
Brooks K,Diero L,DeLong A,Balamane M,Reitsma M,Kemboi E,Orido M,Emonyi W,Coetzer M,Hogan J,Kantor R |
|
Evidence
|
Other common (>20%) RT mutations were NRTI-associated M184V/I (27/35, 77%) and NNRTI-associated Y181C/G/Y (22/35, 63%), G190A/S (13/35, 37%) and K103N/S (11/35, 31%). TDF-associated K70E was found in 3/35 (9%) patients, none with TAMs.
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HIV Mutation Detail Information