Mutation Information
Mutation Site
|
Y181I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
NNRTIs |
Country
|
France;Italy |
Literature Information
PubMed PMID
|
31976534
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
The Journal of antimicrobial chemotherapy |
Title
|
Prevalence of doravirine-associated resistance mutations in HIV-1-infected antiretroviral-experienced patients from two large databases in France and Italy. |
Author
|
Soulie C,Santoro MM,Storto A,Abdi B,Charpentier C,Armenia D,Jary A,Forbici F,Bertoli A,Gennari W,Andreoni M,Mussini C,Antinori A,Perno CF,Calvez V,Ceccherini-Silberstein F,Descamps D,Marcelin AG |
Evidence
|
In comparison, the prevalence of the common NNRTI mutations V90I, K101E/P, K103N/S, E138A/G/K/Q/R/S, Y181C/I/V and G190A/E/S/Q were higher (8.9%, 7.9%, 28.6%, 12.6%, 14.2% and 8.9%, respectively).
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