HIV Mutation Detail Information

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Mutation Information
Mutation Site Y181I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype B;CRF01_AE;CRF08_BC;CRF07_BC
Relevant Drug lamivudine (LAM);efavirenz (EFV);nevirapine (NPV)
Country China
Literature Information
PubMed PMID 31922125
Disease HIV infection/AIDS
Published Year 2020
Journal EClinicalMedicine
Title Trend of HIV-1 drug resistance in China: A systematic review and meta-analysis of data accumulated over 17 years (2001-2017).
Author Zuo L,Liu K,Liu H,Hu Y,Zhang Z,Qin J,Xu Q,Peng K,Jin X,Wang JH,Zhang C
Evidence One NRTI-associated (M184V/I) and three NNRTI-associated (K103N/S, Y181C/I and G190A/S) mutations had high percentages in ART-naive and ART-treated individuals, and these mutations conferred high-level resistance to 3TC, EFV and/or NVP.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation