HIV Mutation Detail Information

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Mutation Information
Mutation Site Y181I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug NRTIs
Country Taiwan(China)
Literature Information
PubMed PMID 29892199
Disease HIV infection/AIDS
Published Year 2018
Journal Infection and drug resistance
Title Patterns of emergent resistance-associated mutations after initiation of non-nucleoside reverse-transcriptase inhibitor-containing antiretroviral regimens in Taiwan: a multicenter cohort study.
Author Cheng CY,Tsai MS,Yang CJ,Cheng SH,Sun HY,Chang SF,Su LH,Su YC,Hung CC,Chang SY
Evidence As K65R, Y181C/I, and K103N were the most common RAMs in our patients receiving nNRTI-containing regimens with virological failure, univariate and multivariate logistic regression analyses were performed to identify the factors associated with these emergent RAMs.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation