HIV Mutation Detail Information

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Mutation Information

Mutation Site	Y181I
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NNRTIs
Country	Africa;Asia;Europe;North and South America

Literature Information

PubMed PMID	20532178
Disease	HIV infection/AIDS
Published Year	2010
Journal	PloS one
Title	Prevalence and clinical significance of HIV drug resistance mutations by ultra-deep sequencing in antiretroviral-naïve subjects in the CASTLE study.
Author	Lataillade M,Chiarella J,Yang R,Schnittman S,Wirtz V,Uy J,Seekins D,Krystal M,Mancini M,McGrath D,Simen B,Egholm M,Kozal M
Evidence	Sixteen subjects (11.3%) had non-nucleoside reverse transcriptase inhibitor (NNRTI) TDR; of these, 15 had one or more of K103N, Y181C/I or G190A/E.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation