Mutation Information
Mutation Site
|
Y181C |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
NNRTIs |
Literature Information
PubMed PMID
|
32643196
|
Published Year
|
2020 |
Journal
|
Protein science : a publication of the Protein Society |
Title
|
Structural investigation of 2-naphthyl phenyl ether inhibitors bound to WT and Y181C reverse transcriptase highlights key features of the NNRTI binding site. |
Author
|
Duong VN,Ippolito JA,Chan AH,Lee WG,Spasov KA,Jorgensen WL,Anderson KS |
Evidence
|
Structural investigation of 2-naphthyl phenyl ether inhibitors bound to WT and Y181C reverse transcriptase highlights key features of the NNRTI binding site.
|
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