HIV Mutation Detail Information

> Y181C Search Result


Mutation Information
Mutation Site Y181C
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Viral Reference AF004885; AF069670; U51190; AF484509; AF286238; AF286237; K03455; AY173951; AY423387; AY331295; U46016; U52953; AF067155; AY772699; K03454; U88824; AY371157; AY253311; AF005494; AF077336; AF075703; AJ249238; AJ249236; AJ249237; AY371158; AF377956; AF061642; AF061640; AF084936; U88826
Relevant Drug NNRTIs
Country Russia
Literature Information
PubMed PMID 32331438
Disease HIV infection/AIDS
Published Year 2020
Journal Viruses
Title HIV-1 Sub-Subtype A6: Settings for Normalised Identification and Molecular Epidemiology in the Southern Federal District, Russia.
Author Schlösser M,Kartashev VV,Mikkola VH,Shemshura A,Saukhat S,Kolpakov D,Suladze A,Tverdokhlebova T,Hutt K,Heger E,Knops E,Böhm M,Di Cristanziano V,Kaiser R,Sönnerborg A,Zazzi M,Bobkova M,Sierra S
Evidence In non-A6 isolates, K103NRT or Y181CRT are preferentially detected after efavirenz exposure while G190SRT is rarely observed, probably due to high costs in replication capacity (in the subtype B context, 20% compared to the wt).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation