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Mutation Information
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Mutation Site
|
Y181C |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
AF004885;
AF069670;
U51190;
AF484509;
AF286238;
AF286237;
K03455;
AY173951;
AY423387;
AY331295;
U46016;
U52953;
AF067155;
AY772699;
K03454;
U88824;
AY371157;
AY253311;
AF005494;
AF077336;
AF075703;
AJ249238;
AJ249236;
AJ249237;
AY371158;
AF377956;
AF061642;
AF061640;
AF084936;
U88826 |
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Relevant Drug
|
NNRTIs |
|
Country
|
Russia |
Literature Information
|
PubMed PMID
|
32331438
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Viruses |
|
Title
|
HIV-1 Sub-Subtype A6: Settings for Normalised Identification and Molecular Epidemiology in the Southern Federal District, Russia. |
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Author
|
Schlösser M,Kartashev VV,Mikkola VH,Shemshura A,Saukhat S,Kolpakov D,Suladze A,Tverdokhlebova T,Hutt K,Heger E,Knops E,Böhm M,Di Cristanziano V,Kaiser R,Sönnerborg A,Zazzi M,Bobkova M,Sierra S |
|
Evidence
|
In non-A6 isolates, K103NRT or Y181CRT are preferentially detected after efavirenz exposure while G190SRT is rarely observed, probably due to high costs in replication capacity (in the subtype B context, 20% compared to the wt).
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HIV Mutation Detail Information