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Mutation Information
|
Mutation Site
|
Y181C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NNRTIs |
|
Country
|
Tanzania |
Literature Information
|
PubMed PMID
|
31929566
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
PloS one |
|
Title
|
High failure rates of protease inhibitor-based antiretroviral treatment in rural Tanzania - A prospective cohort study. |
|
Author
|
Bircher RE,Ntamatungiro AJ,Glass TR,Mnzava D,Nyuri A,Mapesi H,Paris DH,Battegay M,Klimkait T,Weisser M,KIULARCO study group. |
|
Evidence
|
The most common NNRTI mutation was K103NS, detected in 29 (51.8%) adults and 7 (36.8%) children. Additionally, Y181CIV was found in 15 (26.8%) and 4 (21.1%), E138KAQG in 10 (17.9%) and 4 (21.1%) and G190ASEQ in 12 (21.4%) and 5 (26.3%) adults and children, respectively.
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HIV Mutation Detail Information