|
Mutation Information
|
Mutation Site
|
Y181C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B |
|
Relevant Drug
|
NRTIs |
Literature Information
|
PubMed PMID
|
31591964
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
|
Journal
|
eLife |
|
Title
|
Epistasis and entrenchment of drug resistance in HIV-1 subtype B. |
|
Author
|
Biswas A,Haldane A,Arnold E,Levy RM |
|
Evidence
|
The observed vs predicted frequencies are shown for primary drug-resistance mutations V82A occurring in response to PIs in HIV-1 protease (A);N155H occurring in response to INSTIs in HIV-1 IN (B);M184V occurring in response to NRTIs in HIV-1 reverse transcriptase (C);and Y181C/G occurring in response to NNRTIs in HIV-1 reverse transcriptase (D).
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HIV Mutation Detail Information