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Mutation Information
|
Mutation Site
|
Y181C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NNRTIs |
|
Country
|
Uganda |
Literature Information
|
PubMed PMID
|
31257432
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
|
Journal
|
The Journal of antimicrobial chemotherapy |
|
Title
|
Rates of HIV-1 virological suppression and patterns of acquired drug resistance among fisherfolk on first-line antiretroviral therapy in Uganda. |
|
Author
|
Omooja J,Nannyonjo M,Sanyu G,Nabirye SE,Nassolo F,Lunkuse S,Kapaata A,Segujja F,Kateete DP,Ssebaggala E,Bbosa N,Aling E,Nsubuga RN,Kaleebu P,Ssemwanga D |
|
Evidence
|
The most prevalent NRTI mutations were M184V/I (53.6%), K65R (17.5%) and thymidine analogue mutations (TAMs) were present in 21.6% of VF cases. The most prevalent NNRTI mutations were K103N (39.2%), Y181C (19.6%) and G190A (15.5%) (Figure 3).
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HIV Mutation Detail Information