HIV Mutation Detail Information

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Mutation Information

Mutation Site	Y181C
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NNRTIs
Country	Cameroon

Literature Information

PubMed PMID	30577760
Disease	HIV infection/AIDS
Published Year	2018
Journal	BMC pregnancy and childbirth
Title	Rates of HBV, HCV, HDV and HIV type 1 among pregnant women and HIV type 1 drug resistance-associated mutations in breastfeeding women on antiretroviral therapy.
Author	Torimiro JN,Nanfack A,Takang W,Keou CK,Joyce AN,Njefi K,Agyingi K,Domkam I,Takou D,Moudourou S,Sosso S,Mbu RE
Evidence	Of the 40 women on antiretroviral therapy (ART), 9 had at least one major resistance-associated mutation (RAM, 22.5%) to NRTI, NNRTI or PI. Of these M184 V (12.5%), K70R (10.0%), K103 N (12.5%), Y181C (10.0%), M46 L (2.5%) and L90 M (2.5%) were most frequently identified, suggesting resistance to lamivudine, nevirapine, efavirenz and zidovudine.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation