HIV Mutation Detail Information

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Mutation Information
Mutation Site Y181C
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug NNRTIs
Country India
Literature Information
PubMed PMID 30477526
Disease HIV infection/AIDS
Published Year 2018
Journal AIDS research and therapy
Title Long-term virological outcome in children receiving first-line antiretroviral therapy.
Author Chandrasekaran P,Shet A,Srinivasan R,Sanjeeva GN,Subramanyan S,Sunderesan S,Ramesh K,Gopalan B,Suresh E,Poornagangadevi N,Hanna LE,Chandrasekar C,Wanke C,Swaminathan S
Evidence K103N (48%), Y181C (37%), G190A/S (25%), Y188C/L (10%), V106M/A (8%), K65R (8%) and L100I (4%) were the major NNRTI DRMs observed in these 52 children (Fig. 3). 

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation