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Mutation Information
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Mutation Site
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Y181C |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Relevant Drug
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abacavir (ABC);zidovudine (AZT);stavudine (D4T);didanosine (DDI);emtricitabine (FTC);emtricitabine (FTC);lamivudine (LAM);tenofovir (TDF);efavirenz (EFV);etravirine(ETR);nevirapine (NPV);rilpivirine (RPV) |
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Country
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India |
Literature Information
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PubMed PMID
|
30315192
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Disease
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HIV infection/AIDS
|
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Published Year
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2018 |
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Journal
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Scientific reports |
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Title
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Antiretroviral resistance, genotypic characterization and origin of Human Immunodeficiency Virus among the infected wives of Intravenous drug users in Manipur. |
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Author
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Sharma AL,Singh TR,Singh LS |
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Evidence
|
The common DRMs found among the ART naive patients were targeted at (i) NRTI positions: M184V (21.4%, 3/14), K219Q (14.2%, 2/14) and K65R, Y115F and T215F (7.1% each, 1/14) (ii) NNRTI positions: Y181C (14.2%, 2/14) and K103N, G190A and Y188L (7.1% each, 1/14) and (iii) protease inhibitors positions: I54V, L76V and I84V (7.1% each,1/14).
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HIV Mutation Detail Information