|
Mutation Information
|
Mutation Site
|
Y181C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NRTIs |
|
Country
|
Taiwan(China) |
Literature Information
|
PubMed PMID
|
29892199
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
Infection and drug resistance |
|
Title
|
Patterns of emergent resistance-associated mutations after initiation of non-nucleoside reverse-transcriptase inhibitor-containing antiretroviral regimens in Taiwan: a multicenter cohort study. |
|
Author
|
Cheng CY,Tsai MS,Yang CJ,Cheng SH,Sun HY,Chang SF,Su LH,Su YC,Hung CC,Chang SY |
|
Evidence
|
The most common emergent RAMs to NRTIs were M184V/I (42.3%) and K65R (28.2%), and those to nNRTIs were Y181C (42.3%), K103N (15.5%), G190A/E/Q (12.7%), V179D/E (12.7%), and V108I (9.9%).
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HIV Mutation Detail Information